Working with WHI Data

WHI Trials

WHI Data Collection and Procedures

Help Using the WHI Data Files

Data resources publicly available

WHI Data Dictionaries

Annually WHI creates and releases a cumulative dataset for analysis. While the data files are only available to investigators with approved paper proposals, the corresponding data dictionaries provide a directory of the available variables, including their distributions within the study population.

Query Builder

The Query Builder was designed to help stimulate ideas for WHI data and biospecimen use. Queries can be based on study components, demographics, outcomes, specimen availability, test results and more.

See this introductory video to learn how to use the query builder.

Annual Progress Reports

Progress reports are annual summaries of the cumulative data at a specific point in time. They may be the easiest way to locate quick counts in the WHI data.

Specimen Test Results

WHI maintains a database of specimen results performed by WHI and ancillary studies.

  • This page lists the Blood and Urine tests already completed and their QA and summary statistics.
  • The query builder can help determine how many participants with a specific test result.

Genotyping Data

A subset of WHI participants have genotype data available through dbGaP or TOPMed. See this page for more detail on the genomic data available.

Ancillary Study Data

Ancillary studies collect data not normally collected by the WHI. Often these are specimen or genomic tests whose results are added to the WHI data files. If new survey, clinical measurement, or intervention data is collected, the data files and dictionaries are created by the ancillary study investigators and sent to the WHI. Use this listing to find the studies with these data.

Biologic Specimen and Data Repository Information

Coordinating Center (BioLINCC)

A subset of the WHI Clinical Trial a​nd Observational Study data is available through BioLINCC. You do not need a WHI collaborator to access these datasets.

Resources available for those with approved paper proposals

WHI Dataset Files

If you plan to conduct the analysis yourself, a signed Data Use Agreement must be submitted to the CCC at Once completed, you will be provided access to download WHI datasets (note that a WHI login account with data access is required).

Virtual Data Enclave and Medicare Data

The Virtual Data Enclave is a secure environment where approved investigators can perform analyses on data that is too sensitive to be released in our normal datasets (see sensitive data not included in investigator datasets). Medicare data on WHI participants is also available in the Virtual Data Enclave.

This is a free resource for approved investigators. Contact the WHI Coordinating Center to set up an account to use these data.

More details…