WHI Questionnaires

If an event that needed adjudication was found on the form 33, a 33D was collected.

*All participants who previously reported diagnosis of breast cancer

*For E+P, when intervention stopped July 9, 2002.
For E-Alone, when intervention stopped in February 2004.

*At CaD study close-out October 2004-March 2005.

Collected every 6 months for CT ppts

If an event that needed adjudication was found on the form 33, a 33D was collected.

*HT cohort aged 65 and over.

*Initiated in 2002 and collected once from all CT and OS participants at next routine contact.

*For E+P participants on study through July 8, 2002, when intervention was stopped; administration began in March 2003.

entered if ppt needed to modify their study medication dosage

*For all E-Alone participants; administered twice:

*Year 2: 30% cross sectional 33% rotating subsample starting in the year 2000, such that for year 3 and each subsequent year each DM participant received an FFQ at once every 3 years.

Administered as indicated and as needed to manage unexpected bleeding. Not required after July 9, 2002, when intervention was stopped.

*5% E+P participants with uterus

*Done only if endometrial aspiration could not be done or was refused.

*Optional for DM participants.

*Collected for ppts enrolled at 3 clinical centers or about 6-7% of total WHI. Yr1 collection limited to CT

*Sample was selected from the HT and DM > 65 years old.

*6% CT subsample. Year 6 collection was plasma only

*% - Collected at 3 BMD clinical centers. Year 9 collection was for 25% of OS ppts

*For OS participants who did not reach Year 7 by Closeout