Vision

WHI strives to improve health through research on risk factors, prevention, and early detection of serious health conditions, so postmenopausal women thrive.

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VisionVision

Impacting lives through groundbreaking research

Impacting lives through groundbreaking research
161,000 +study participants
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5.3 millionspecimen vials collected and documented
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12,600fewer cases of breast cancer each year as a result of WHI research
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The Women’s Health Initiative is a landmark study that has had a huge impact on medical practice and public health.

— Gary H. Gibbons, M.D., NHLBI Director
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2,312papers published to date using WHI datapapers published using WHI data
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WHI News

2023 WHI Investigators Meeting

2023 WHI Investigators Meeting

3/14/2023
Registration is now open for the 2023 WHI Investigators Meeting! Please see the attached link for registration information. More details to follow.
WHI Response to NYT article "Women have been misled about menopause"

WHI Response to NYT article "Women have been misled about menopause"

2/15/2023
On February 1st, the NYT Magazine published an article describing some perimenopausal women’s struggles with menopause and the role of hormone therapy in relieving symptoms. The WHI hormone trials are cast in a rather unfavorable light in this article, mostly because the trial was not designed to address the concerns of perimenopausal women. The WHI Steering Committee has written a letter to the editor of the NYT in response, which can be found below.
Remembering Dr. Lewis Kuller - MEMORIAL INFO AVAILABLE

Remembering Dr. Lewis Kuller - MEMORIAL INFO AVAILABLE

2/2/2023
What a difficult year this has been for us. Sadly, we must inform you of the passing of one of the major intellectual leaders in the WHI. Dr. Lewis Kuller passed away last night after some months of declining health.
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Recent Publications

Association of social support with mild cognitive impairment and dementia among older women: Women’s Health Initiative Memory Study

Alexander Posis et al., 2023/undefined PubMed #36565123

Validating a model for predicting breast cancer and non-breast cancer death in women aged 55 and older

Mara Schonberg et al., 2023/9 PubMed #37676833

Association between insomnia, stress events and other psychosocial factors and incident atrial fibrillation in postmenopausal women: Insights from the Women's Health Initiative

Susan Zhao et al., 2023/9 PubMed #37646212

Changes in physical function in older women with endometrial cancer with or without adjuvant therapy

Allison Quick et al., 2023/9 PubMed #37668940

Previous fracture and subsequent fracture risk: A meta-analysis to update FRAX

John A. Kanis et al., 2023/8 PubMed #37566158

Association of later life weight changes with survival to ages 90, 95, and 100: The Women’s Health Initiative

Aladdin Shadyab et al., 2023/8 PubMed #37642339

Association of maternal birth weight and maternal preterm birth with subsequent risk for adverse reproductive outcomes: The Women’s Health Initiative

Cassandra Spracklen et al., 2023/8 PubMed #37549575

Bilateral oophorectomy and colorectal cancer incidence and mortality in the Women's Health Initiative

Mihae Song et al., 2023/8 PubMed #37566400

Adverse pregnancy outcomes and risk of type 2 diabetes in the Women’s Health Initiative

Kexin Zhu et al., 2023/7 PubMed #37490991

Birth weight, adult body size, and risk of colorectal cancer

Le Su et al., 2023/7 PubMed #37413805

Biomarkers of glucose homeostasis as mediators of the relationship of body mass index and waist circumference with COVID-19 outcomes among postmenopausal women from the Women’s Health Initiative

Hind Beydoun et al., 2023/7 PubMed #37523800

Associations of dietary cholesterol and fat, blood lipids, and risk for dementia in older women vary by APOE genotype

Ira Driscoll et al., 2023/7 PubMed #37438877

Pre-diagnosis lipid levels and mortality after obesity-related cancer diagnosis in the Women’s Health Initiative cardiovascular disease biomarker cohort

Gayane Hovsepyan et al., 2023/6 PubMed #37381978

Life events, caregiving, and risk of autoimmune rheumatic diseases in the Women's Health Initiative Observational Study

Christine Parks et al., 2023/5 PubMed #37230960

Metabolomics Biomarkers for Fatty Acid Intake and Biomarker-Calibrated Fatty Acid Associations with Chronic Disease Risk in Postmenopausal Women

Ross Prentice et al., 2023/5 PubMed #37178978

Factors associated with long-term gastrointestinal symptoms in colorectal cancer survivors in the women's health initiatives (WHI study)

Claire J. Han et al., 2023/5 PubMed #37205667

Long-term exposure to ambient particulate matter and stroke etiology: Results from the Women’s Health Initiative

Erin Kulick et al., 2023/5 PubMed #36813070

Race and Ethnicity and Fracture Prediction Among Younger Postmenopausal Women in the Women's Health Initiative Study

Carolyn Crandall et al., 2023/5 PubMed #37213092

The co-occurrence and cumulative prevalence of hypertension, rheumatoid arthritis, and hypothyroidism in preterm-born women in the Women's Health Initiative

Pamela Brewer et al., 2023/5 PubMed #37198934

A longitudinal study of sleep habits and leukemia incidence among postmenopausal women

Shang Hui et al., 2023/5 PubMed #37191332

Metabolomics-Based Biomarker for Dietary Fat and Associations with Chronic Disease Risk in Postmenopausal Women

Ross Prentice et al., 2023/5 PubMed #37245660

Neighborhood socioeconomic status, green space, and walkability and risk for falls among postmenopausal women: The Women’s Health Initiative

Marilyn Wende et al., 2023/5 PubMed #37149415

Body size over the adult life course and the risk of colorectal cancer among postmenopausal women

Le Su et al., 2023/5 PubMed #37199248

Diabetes, metformin use and risk of non-Hodgkin's lymphoma in postmenopausal women: A prospective cohort analysis in the Women's Health Initiative

Zikun Wang et al., 2023/4 PubMed #36444502

Association of Preterm Birth With Prevalent and Incident Hypertension, Early-Onset Hypertension, and Cardiovascular Disease in the Women's Health Initiative

Pamela Brewer et al., 2023/4 PubMed #36791524

Quantifying structural racism in cohort studies to advance prospective evidence

Shawna Follis et al., 2023/4 PubMed #37207111

Demographic, Health and Lifestyle Factors Associated with the Metabolome in Older Women

Daniel Raftery et al., 2023/4 PubMed #37110172

Assessment of immune cell profiles among post-menopausal women in the Women's Health Initiative using DNA methylation-based methods

Karl Kelsey et al., 2023/4 PubMed #37118842

Associations of maternal preterm birth with subsequent risk for type 2 diabetes in women from the women's health initiative

Cassandra Spracklen et al., 2023/4 PubMed #37114530

Development and validation of new predictive equations for the resting metabolic rate of older adults aged >65 y

Judi Porter et al., 2023/4 PubMed #37054885

Want to view more works by WHI investigators? Visit our publications page