WHI strives to improve health through research on risk factors, prevention, and early detection of serious health conditions, so postmenopausal women thrive.

Learn more

Impacting lives through groundbreaking research

Impacting lives through groundbreaking research
161,000 +study participants
Dive into the dataRead More
5.3 millionspecimen vials collected and documented
Explore available biospecimensSee Details
12,600fewer cases of breast cancer each year as a result of WHI research
Read the paperSee Manuscript

The Women’s Health Initiative is a landmark study that has had a huge impact on medical practice and public health.

— Gary H. Gibbons, M.D., NHLBI Director
See the impactReview Timeline
2,380papers published to date using WHI datapapers published using WHI data
Browse the publication database View Papers

WHI News

WHI Highlighted at 75th Anniversary of NHLBI

WHI Highlighted at 75th Anniversary of NHLBI

WHI Profile in celebration of NHLBI’s 75th anniversary, featuring a WHI Participant
Radon Exposure and Stroke Risk in the Women's Health Initiative

Radon Exposure and Stroke Risk in the Women's Health Initiative

A paper studying the association between radon and stroke in woman has been published in the online issue of Neurology, the medical journal of the American Academy of Neurology
2023 WHI Investigators Meeting

2023 WHI Investigators Meeting

Registration is now open for the 2023 WHI Investigators Meeting! Please see the attached link for registration information. More details to follow.
Want more stories? Please check out the news archive. Have news to share? Please send us an e-mail!

Recent Publications

Correlates of physical activity and sedentary behavior among cancer survivors and Cancer-Free Women: The Women’s Health Accelerometry Collaboration

Samantha Schilsky et al., 2024/4 PubMed #38573893

20-year depressive symptoms, dementia, and structural neuropathology in older women

Andrew J. Petkus et al., 2024/4 PubMed #38591250

Plasma oxysterols are associated with serum lipids and dementia risk in older women

Michelle Dunk et al., 2024/4 PubMed #38574442

Physical function trajectory after wrist or lower arm fracture in postmenopausal women: Results from the Women’s Health Initiative Study

Carolyn Crandall et al., 2024/3 PubMed #38459975

Heart failure risk among African American Women with an ICAM1 Missense variant

Ravi Patel et al., 2024/3 PubMed #38530700

Relationship of psychotropic medication use with physical function among postmenopausal women

Hind Beydoun et al., 2024/3 PubMed #38517642

Depressive symptoms and antidepressant use in relation to white blood cell count among postmenopausal women from the Women’s Health Initiative

Hind Beydoun et al., 2024/3 PubMed #38514652

Longitudinal Associations Between Optimism and Objective Measures of Physical Functioning in Women

Hayami K. Koga et al., 2024/3 PubMed #38506825

Low physical function post-cancer diagnosis is associated with higher mortality risk in postmenopausal women

Paola Gonzalo Encabo et al., 2024/3 PubMed #38449287

Long-Term Effect of Randomization to Calcium and Vitamin D Supplementation on Health in Older Women : Postintervention Follow-up of a Randomized Clinical Trial

Cynthia Thomson et al., 2024/3 PubMed #38467003

Infertility and risk of postmenopausal breast cancer in the Women’s Health Initiative

Leslie Farland et al., 2024/3 PubMed #38459395

Fatty acid intake and polyunsaturated fatty acid biomarkers and risk of total knee or hip arthroplasty among older women in the Women’s Health Initiative

Tonya Orchard et al., 2024/2 PubMed #38412867

Biomarker-assessed total energy intake and its association with all-cause mortality in postmenopausal women

Ross Prentice et al., 2024/2 PubMed #38428741

Photosensitizing antihypertensive medication and risk of skin cancer among postmenopausal women

Alexander Hou et al., 2024/2 PubMed #38345266

Prevalence of frequent premature ventricular contractions and nonsustained ventricular tachycardia in older women screened for atrial fibrillation in the Women's Health Initiative

Sofia Gomez et al., 2024/2 PubMed #38403238

Improving polygenic risk prediction in admixed populations by explicitly modeling ancestral-specific effects via GAUDI

Yun Li et al., 2024/2 PubMed #38310129

Dietary intervention favorably influences physical functioning: the Women's Health Initiative randomized Dietary Modification trial

Rowan Chlebowski et al., 2024/2 PubMed #38395355

Associations of accelerometer-measured physical activity and sedentary behavior with incident clinical osteoporotic fractures among older women: the OPACH study

Steve Nguyen et al., 2024/2 PubMed #38410939

Practical considerations for sandwich variance estimation in two-stage regression settings

Lillian Boe et al., 2024/2 PubMed #38012109

Traditional Mexican dietary pattern and cancer risk among women of Mexican descent

Nicole Lorona et al., 2024/2 PubMed #38305935

Using simultaneous regression calibration to study the effect of multiple error-prone exposures on disease risk utilizing biomarkers developed from a controlled feeding study

Yiwen Zhang et al., 2024/2 PubMed #38313601

Radon exposure and incident stroke risk in the Women’s Health Initiative

Sophie Buchheit et al., 2024/2 PubMed #38546022

Engagement With Remote Delivery Channels in a Physical Activity Intervention for Senior Women in the US

Andrea Mendoza-Vasconez et al., 2024/2 PubMed #38344760

Accelerometer-measured physical activity, sedentary time and heart failure risk in women ages 63-99 years

Michael LaMonte et al., 2024/2 PubMed #38381446

Comparison of PM2.5 air pollution exposures and health effects associations using 11 different modeling approaches in the Women's Health Initiative Memory Study (WHIMS)

Melinda Power et al., 2024/1 PubMed #38226465

Alcohol consumption and the diversity of the oral microbiome in postmenopausal women

Amy Millen et al., 2024/1 PubMed #37913907

Dietary patterns and epigenetic aging in the Women’s Health Initiative

Lindsay Reynolds et al., 2024/1 PubMed #38215906

Dietary carbohydrate intake is associated with the subgingival plaque oral microbiome abundance and diversity in a cohort of postmenopausal women

Amy Millen et al., 2024/1 PubMed #35173205

Radon Exposure, clonal Hematopoiesis, and stroke susceptibility in the Women's Health Initiative

Kurt Anthony et al., 2024/1 PubMed #38170948

Association of social support with mild cognitive impairment and dementia among older women: Women’s Health Initiative Memory Study

Alexander Posis et al., 2023/undefined PubMed #36565123

Want to view more works by WHI investigators? Visit our publications page