Ancillary Studies
Major Ancillary Studies
These are a few of the larger WHI ancillary studies. See a list of all studies
COcoa Supplement and Multivitamin Outcomes Study (COSMOS)
A clinical trial that will randomize approximately 22,000 men and women across the U.S. The study will investigate whether taking daily supplements of cocoa flavanols (600 mg/day) or a common multivitamin reduces the risk for developing heart disease, stroke, and cancer.
WHI Life and Longevity After Cancer
The WHI Life and Longevity After Cancer (LILAC) Study was funded by the National Cancer Institute with study goals of enrolling WHI participants who have been diagnosed with cancer into a cancer survivorship cohort and then examining factors that may affect life and longevity among women who have been diagnosed with cancer.
WHI Memory Study (WHIMS)
WHIMS was an ancillary study to the WHI Hormone Trials and enrolled 7,427 women aged 65 years and older. WHIMS investigated the effects of hormone supplementation on risk of probable dementia and any cognitive impairment and on changes in global cognition over time.
Objective Physical Activity and Cardiovascular Health in Older Women (OPACH)
The OPACH study was an ancillary study of the WHI Long Life Study. Long Life Study participants who were ambulatory were concurrently invited to join the OPACH study. The goal of OPACH was to increase the understanding of the health benefits and risks of physical activity, specifically with cardiovascular events and incident falls.
Women’s Health Initiative Sleep Hypoxia Effects on Resilience – WHISPER
The WHISPER study examines whether sleep-disordered breathing and the resulting low blood oxygen are associated with increased risks of health events, including heart attack, stroke, heart failure, cancer, and cognitive decline.
All Funded and Approved Studies
Id | Name | PI Name | Status | Funding Agency | Grant Number | Datafiles |
|---|---|---|---|---|---|---|
| Id753 | NameTOPMed X01 – Omics resources for Women's Health Initiative African American women cardiovascular health research | PI NameKooperberg,Charles | StatusApproved | Funding Agency | Grant Number | DatafilesN |
| Id752 | NameClonal hematopoiesis of indeterminate potential in aging and exceptional longevity | PI NameReiner,Alexander | StatusApproved | Funding Agency | Grant Number | DatafilesN |
| Id748 | NameCirculating immune checkpoint proteins and the early detection of gynecologic cancers | PI NameMichels,Kara | StatusApproved | Funding Agency | Grant Number | DatafilesN |
| Id747 | NameMetabolomics and the Prospective analysis of age-related macular degeneration and the structural integrity of the retina | PI NameMillen,Amy | StatusApproved | Funding Agency | Grant Number | DatafilesN |
| Id742 | NameTRAJECTORY Study: Changing generational trajectory of cardiovascular disease with the adult children and grandchildren of the Women’s Health Initiative study | PI NameBreathett,Khadijah | StatusFunded | Funding Agency | Grant Number | DatafilesN |
| Id741 | NameImpact of genetic susceptibility on colorectal tumor immune profile | PI NameThomas,Claire | StatusApproved | Funding Agency | Grant Number | DatafilesN |
| Id740 | NameFracture risk assessment among older adults with diabetes | PI NameLee,Richard | StatusApproved | Funding Agency | Grant Number | DatafilesN |
| Id739 | NameCardiovascular disease, preeclampsia, and fetal microchimerism | PI NameShree,Raj | StatusApproved | Funding Agency | Grant Number | DatafilesN |
| Id738 | NameBlood protein biomarkers for colorectal cancer etiology, prevention, and disparity | PI NameMurphy,Neil | StatusApproved | Funding Agency | Grant Number | DatafilesN |
| Id737 | NameDefining the clinical characteristics of inflammatory and insulinemic dietary patterns using feeding study dietary data and blood biomarkers | PI NameTabung,Fred | StatusApproved | Funding Agency | Grant Number | DatafilesN |
