BA1 - Ancestry association analyses of WHI traits
Data Dictionaries and Study Documentation
This section displays all study-related data dictionaries and study-related files. The investigators for this study will upload the datasets, data dictionaries, and other study-related files. Study-related files will be made available to the public one year after the completion of the ancillary study, with the exception of the datasets, which will only be available to those with a Data Distribution Agreement. Those will be available to those with permission to download and will appear as a download link next to the data dictionary
Data Dictionaries
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Study Documents
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| NameBAA 01 case-control Summary.doc | Description |
Related Papers
Relationship between hypertension and admixture in post-menopausal African American and Hispanic American Women
To assess the relationship between ethnicity and hypertension using individual admixture and blood pressure measurements, we performed a cross-sectional study of African American and Hispanic American (HA) women enrolled in the Women's Health Initiative. The admixture odds ratio for systolic and diastolic hypertensive risk was determined using linear regression models in which the proportional measurements of European (EUR), sub-Saharan African (AFR) and Amerindian (AMI) admixture was analyzed u...
Keywords: Blood Pressure; Hypertension; Body Mass Index; Ethnicity; African American; Hispanic Americans; Genetics
Related Studies: BA1
Relationship of pain and ancestry in African American women
African Americans are reported to be more sensitive to pain than European Americans. Pain sensitivity has been shown to be genetically linked in animal models and is likely to be in humans.Exactly, 11,239 self-identified African American post-menopausal women enrolled in the Women's Health Initiative had percentage African ancestry determined by ancestry informative markers, ''Pain Construct'' measurements and covariate information. They answered five questions about specific types and location ...
Related Studies: BA1
Stronger bone correlates with African admixture in African American women
Osteoporosis affects all populations, but the risk for low bone density and fracture varies greatly by self-reported race and ethnicity. In this article, the relationship between measured percent African admixture and hip structural geometry, estimated from the hip structural analysis (HSA) program, was examined in a subcohort of the Women's Health Initiative (WHI). The study sample included 793 African-American women and 8559 non-Hispanic white women. All the participants were postmenopausal, b...
Keywords: Aging; Hip Geometric Structure; Longitudinal Change; Ethnicity
Relationship between adiposity and admixture in African-American and Hispanic-American women
The objective of this study was to investigate whether differences in admixture in African-American (AFA) and Hispanic-American (HA) adult women are associated with adiposity and adipose distribution.The proportion of European, sub-Saharan African and Amerindian admixture was estimated for AFA and HA women in the Women's Heath Initiative using 92 ancestry informative markers. Analyses assessed the relationship between admixture and adiposity indices.The subjects included 11 712 AFA and 5088 HA s...
Keywords: Obesity; Body Mass Index; Waist Circumference; Hip Circumference; Trunk Fat; Ethnicity; African American; Hispanic Americans; Genetics
Related Studies: BA1
Relationship between hysterectomy and admixture in African American women
Most studies suggest that hysterectomies are more common in African American women than in other ethnic groups. To assess this ethnic surgical disparity in a novel way, our main goal was to determine whether admixture (the proportion of sub-Saharan African or European origin in individuals) is associated with hysterectomy frequency in African American women in the Women's Health Initiative.In this retrospective study, we used ancestry informative single nucleotide polymorphisms to estimate admix...
Keywords: Hysterectomy; Body Mass Index; Waist To Hip Ratio; Ethnicity; African American; Hispanic Americans; Admixture; Genetics
Related Studies: BA1
Energy-adjusted dietary inflammatory index and diabetes risk in postmenopausal Hispanic Women
Background: Type 2 diabetes is a major public health concern in the United States and worldwide. The dietary inflammatory index (DII) and the energy-adjusted DII (E-DII) are tools that assess dietary inflammation. Previous evidence suggests that obesity can modify the association between inflammation and disease. Objective: The aim of this study was to evaluate the association between the DII/E-DII and incident diabetes in self-identified Hispanic women from the Women's Health Initiative (WHI). ...
Keywords: Diabetes; Dietary Inflammatory Index; Inflammation; Latino; Hispanic.
Related Studies: BA1
Genetic admixture and cardiovascular disease risk in postmenopausal Hispanic women
Background: Hispanics are a heterogeneous population with differences in the prevalence of cardiovascular disease (CVD) and its related risk factors among ethnic sub-groups. This study evaluated the association of genetic admixture and CVD in self-identified Hispanic women from the Women's Health Initiative (WHI). Methods: Data came from the WHI Observational Study and the Clinical Trial Components conducted among postmenopausal women. The CVD outcomes included coronary heart disease (CHD) and s...
Keywords: Cardiovascular Disease; Admixture; Latino; Hispanic American; Stroke; Venous Thrombosis; Coronary Heart Disease
Related Studies: BA1
Genetic Admixture and Social/Environmental Factors for Breast Cancer among Postmenopausal African American Women in the Women’s Health Initiative
Keywords: Genetic Admixture; Breast Cancer; Risk Factors; Post-Menopausal Women; Racial Disparities
Related Studies: BA1
Relationship between diabetes risk and admixture in postmenopausal African American and Hispanic American women
Type 2 diabetes is more prevalent in African-Americans (AFAs) and Hispanic-Americans (HAs) than in European-Americans. We assessed whether continental admixture was correlated with diabetes risk in these high-risk groups.We estimated the proportion of sub-Saharan African (AFR), Amerindian (AMI) and European admixture using 92 ancestry-informative marker genotypes in 16,476 AFA and HA women from the Women's Health Initiative. Cox regression models were used to examine the association between admi...
Keywords: Body Mass Index; Waist To Hip Circumference Ratio; Ethnicity; African American; Hispanic Americans; Admixture; Genetics
Related Studies: BA1
Dietary inflammatory index and cardiovascular disease risk in Hispanic women from the Women's Health Initiative
Background: To evaluate the association between the dietary inflammatory index (DII®) and incident cardiovascular disease (CVD) in Hispanic women from the Women's Health Initiative (WHI), and to determine if body mass index (BMI) interacted with the DII scores. Methods: Secondary analysis of baseline dietary data and long-term CVD outcomes among 3,469 postmenopausal women who self-identified as Hispanic enrolled in WHI. DII scores were calculated from self-administered food frequency questionnai...
Keywords: Cardiovascular Disease; Dietary Inflammatory Index; Latino; Hispanic American; Stroke; Venous Thrombosis; Coronary Heart Disease
Related Studies: BA1
Relationship between glaucoma and admixture in postmenopausal African-American women
To investigate the association between African admixture and glaucoma prevalence among African American women.Participants included 11616 African American women from the Women's Health Initiative Study (WHI) for whom admixture information was available and included 2548 who self-reported a diagnosis of glaucoma.Glaucoma.Significant association was observed between self-identified glaucoma status and admixture. However, this association was not significant in a model that included neighborhood so...
Keywords: Diabetes; Glaucoma; Vision Loss; Ethnicity; African American; Admixture; Genetics
Related Studies: BA1
Relationship between gallbladder surgery and ethnic admixture in African American and Hispanic American women
The objective of this study was to investigate whether differences in admixture in African American and Hispanic American adult women are associated with differences in gallbladder surgery.Gallbladder surgery history on entry to the Women's Health Initiative's (WHI) study was used as a dichotomous outcome measure for this study. The proportion of European, sub-Saharan African, and Amerindian (AMI) admixture was estimated for 10,841 African American and 4,620 Hispanic American women in WHI using ...
Keywords: Cholecystectomy; Gallstone Removal; Body Mass Index; Waist To Hip Ratio; Ethnicity; African American; Hispanic Americans; Admixture; Genetics
Related Studies: BA1
