AS481 - Cardiovascular disease and aircraft noise exposure

Investigator Names and Contact Information

Junenette Peters (petersj@bu.edu)

Introduction/Intent

Exposure to aircraft noise has been associated with physiological responses and psychological reactions. However, the extent to which exposure to aircraft noise increases the risk of adverse health outcomes is not well understood. In previous work conducted by our Federal Aviation Administration (FAA)-supported Center of Excellence, we leveraged administrative data from the Medicare system to evaluate the association between aircraft noise from 89 airports across the U.S. and cardiovascular hospital admissions among Medicare beneficiaries. Although our findings were robust, our study had several limitations, including reliance on ZIP code resolution address information, limited data on individual risk factors, and International Classification of Disease (ICD)-coded claims. We therefore propose to continue evaluating the health effects of noise exposure in the Women’s Health Initiative (WHI) clinical trials and observational study cohorts, by linking study data to aircraft noise exposures and then estimating their associations with cardiovascular disease (CVD). This proposed cohort study will expand our understanding of the noise-health relationship by: (1) estimating residential exposure to aircraft noise exposures over time to geocoded participant addresses 1993-2012; (2) assessing associations between the exposures and CVD; (3) examining the noise-CVD associations for evidence of thresholds and non-linearity; and finally, (4) determining the number of incident CVD events attributable to noise that could be reduced by decreasing exposures to aircraft noise. As growth in aviation is anticipated, the results of this timely study will inform FAA’s strategies for reducing adverse health effects of aircraft noise and their policy decisions related to threshold setting in the U.S.

SPECIFIC AIMS

The aims of the proposed study are to:

  1. Develop national noise surfaces using Integration Noise Model (INM) modeling.
  2. Assign aircraft noise exposures over time to geocoded participant addresses, 1993-2012.
  3. Estimate associations between the exposures and cardiovascular disease (CVD).
  4. Examine the noise-CVD associations for evidence of thresholds and non-linearity.
  5. Determine the number of incident CVD events attributable to noise that could be reduced by decreasing exposures to aircraft noise.

Related Papers

The impact of aircraft noise on acute sleep disruptions and other sleep problems in the Women’s Health Initiative

Approved Proposal, Costello, Jean et al., 2024/11 MSID: 5225
Keywords: Sleep Disruption; Aircraft Noise; Environmental Influence On Sleep; Stress; Environment
Related Studies: 140, 251, 481

Aircraft noise and clonal hematopoiesis of indeterminate potential

Approved Proposal, Collins, Jason et al., 2019/8 MSID: 3990
Keywords: Chip; Clonal Hematopoiesis; Aircraft Noise; Environment; Cvd
Related Studies: 481, 564

Long-term exposure to aircraft noise and incidence of cardiovascular events in the Women’s Health Initiative

Approved Proposal, Nguyen, Daniel D. et al., 2017/6 MSID: 3396
Keywords: Aircraft Noise; Airport Noise; Cardiovascular Disease; Epidemiology; Noise Exposure
Related Studies: 140, 251, 481

Long-term aircraft noise exposure and risk of hypertension in postmenopausal women

Daniel D. Nguyen et al., 2022/12 PubMed #36502895 MSID: 2685
Background: Studies of the association between aircraft noise and hypertension are complicated by inadequate control for potential confounders and a lack of longitudinal assessments, and existing evidence is inconclusive. Objectives: We evaluated the association between long-term aircraft noise exposure and risk of hypertension among post-menopausal women in the Women's Health Initiative Clinical Trials, an ongoing prospective U.S. Methods: Day-night average (DNL) and night equivalent sound leve...
Keywords: Aircraft Noise; Airport Noise; Blood Pressure; Epidemiology; Noise Exposure
Related Studies: 140, 251, 481

Neighborhood socioeconomic status, green space, and walkability and risk for falls among postmenopausal women: The Women’s Health Initiative

Marilyn Wende et al., 2023/5 PubMed #37149415 MSID: 4068
Purpose: This study estimated associations between neighborhood socioeconomic status (NSES), walkability, green space, and incident falls among postmenopausal women and evaluated modifiers of these associations, including study arm, race and ethnicity, baseline household income, baseline walking, age at enrollment, baseline low physical functioning, baseline fall history, climate region, and urban-rural residence. Methods: The Women's Health Initiative recruited a national sample of postmenopaus...
Keywords: Built Environment; Neighborhood; Falls; Physical Activity; Injury
Related Studies: 140, 220, 251, 252, 264, 315, 442, 481

How neighborhood socioeconomic status, green space, and walkability are associated with risk for fracture among postmenopausal women: The Women’s Health Initiative

Marilyn Wende et al., 2023/7 PubMed #37149415 MSID: 4069
Purpose: This study estimated associations between neighborhood socioeconomic status (NSES), walkability, green space, and incident falls among postmenopausal women and evaluated modifiers of these associations, including study arm, race and ethnicity, baseline household income, baseline walking, age at enrollment, baseline low physical functioning, baseline fall history, climate region, and urban-rural residence. Methods: The Women's Health Initiative recruited a national sample of postmenopaus...
Keywords: Neighborhood Socioeconomic Status; Walkability; Green Space; Fracture; Postmenopausal
Related Studies: 140, 220, 251, 252, 264, 315, 442, 481