W18 - HT Hormone Pretest

Data Dictionaries and Study Documentation

This section displays all study-related data dictionaries and study-related files. The investigators for this study will upload the datasets, data dictionaries, and other study-related files. Study-related files will be made available to the public one year after the completion of the ancillary study, with the exception of the datasets, which will only be available to those with a Data Distribution Agreement. Those will be available to those with permission to download and will appear as a download link next to the data dictionary

Data Dictionaries

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Study Documents

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Namew18 selection summary Additional 08-20-06.docDescription

Related Papers

The effects of postmenopausal hormone therapy on serum estrogen, progesterone, and sex hormone-binding globulin levels in healthy postmenopausal women

Kerstin Edlefsen et al., 2010/3 PubMed #20215977 MSID: 795
Differences in disease outcomes between users and nonusers of hormone therapy (HT) and between users of estrogen therapy (ET) and users of estrogen + progesterone therapy (EPT) may relate to differences in serum hormone concentrations between these populations. In this study, we examined the response of serum hormone levels in healthy postmenopausal women after 1 year of HT.A representative subsample of 200 healthy adherent participants from the active and placebo groups of the Women's Health In...
Keywords: Hormone Therapy; Estrogen; Progesterone; Estradiol; Hormone Levels; Sex Hormone Binding Globulin
Related Studies: W18

Age, body mass, usage of exogenous estrogen, and lifestyle factors in relation to circulating sex hormone-binding globulin concentrations in postmenopausal women

Atsushi Goto et al., 2013/9 PubMed #24048437 MSID: 1218
Circulating concentrations of sex hormone-binding globulin (SHBG) have been associated with cardiovascular diseases, type 2 diabetes, metabolic syndrome, and hormone-dependent cancers; however, correlates of SHBG concentrations are not well understood.We comprehensively investigated correlates of SHBG concentrations among 13 547 women who participated in the Women's Health Initiative and who had SHBG measurements. We estimated study- and ethnicity-specific associations of age, reproductive histo...
Keywords: Plasma Sex Hormone Binding Globulin (Shbg); Dietary Factors
Related Studies: 90, 110, 167, BA7, BA9, BA21, W5, W9, W10, W18

Relation of dietary carbohydrates intake to circulating sex hormone-binding globulin levels in postmenopausal women

Mengna Huang et al., 2017/3 PubMed #28304147 MSID: 2447
BACKGROUND: Low circulating levels of sex hormone-binding globulin (SHBG) have been shown to be a direct and strong risk factor for type 2 diabetes, cardiovascular diseases, and hormone-dependent cancers, although the relation between various aspects of dietary carbohydrates and SHBG levels remains unexplored in population studies. METHODS: Among postmenopausal women with available SHBG measurements at baseline (n = 11,159) in the Women's Health Initiative, we conducted a comprehensive assessmen...
Keywords: Dietary Carbohydrates; Glycemic Index; Glycemic Load; Sex Hormone Binding Globulin (Shbg); Type 2 Diabetes

Circulating SHBG (Sex Hormone-Binding Globulin) and risk of ischemic stroke: Findings from the WHI

Tracy Madsen et al., 2020/2 PubMed #32078494 MSID: 3372
Abstract Background and Purpose- Circulating levels of SHBG (sex hormone-binding globulin) have been inversely linked to obesity, diabetes mellitus, and other cardiometabolic disorders. It remains uncertain whether low SHBG is prospectively predictive of stroke risk, particularly in women. We investigated whether SHBG is associated with risk of incident ischemic stroke (IS) among women in the WHI (Women's Health Initiative). Methods- From an observational cohort of 161 808 postmenopausal women e...
Keywords: Ischemic Stroke; Sex Hormone Binding Globulin; Sex Hormones; Prevention; Sex Differences

Sex hormones, sex hormones binding globulin (SHBG), and risk of ischemic stroke in men and women in WHI and TOPMed Stroke

Approved Proposal, Madsen, Tracy et al., 2020/11 MSID: 4327
Keywords: Stroke; Sex Hormone Binding Globulin; Mendelian Randomization; Single Nucleotide Polymorphisms; Ischemic Stroke
Related Studies: 90, 110, 238, BA7, BA9, BA21, W5, W9, W10, W18

Sex specific stroke risk score in the Women’s Health Initiative

Approved Proposal, Madsen, Tracy et al., 2020/5 MSID: 4211
Related Studies: 90, 110, 167, 238, BA7, BA9, BA21, W9, W10, W18