AS110 - Sex steroid hormones and risk of coronary heart disease: a nested case control study

Data Dictionaries and Study Documentation

This section displays all study-related data dictionaries and study-related files. The investigators for this study will upload the datasets, data dictionaries, and other study-related files. Study-related files will be made available to the public one year after the completion of the ancillary study, with the exception of the datasets, which will only be available to those with a Data Distribution Agreement. Those will be available to those with permission to download and will appear as a download link next to the data dictionary

Data Dictionaries

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Study Documents

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Related Papers

Age, body mass, usage of exogenous estrogen, and lifestyle factors in relation to circulating sex hormone-binding globulin concentrations in postmenopausal women

Atsushi Goto et al., 2013/9 PubMed #24048437 MSID: 1218
Circulating concentrations of sex hormone-binding globulin (SHBG) have been associated with cardiovascular diseases, type 2 diabetes, metabolic syndrome, and hormone-dependent cancers; however, correlates of SHBG concentrations are not well understood.We comprehensively investigated correlates of SHBG concentrations among 13 547 women who participated in the Women's Health Initiative and who had SHBG measurements. We estimated study- and ethnicity-specific associations of age, reproductive histo...
Keywords: Plasma Sex Hormone Binding Globulin (Shbg); Dietary Factors
Related Studies: 90, 110, 167, BA7, BA9, BA21, W5, W9, W10, W18

Circulating SHBG (Sex Hormone-Binding Globulin) and risk of ischemic stroke: Findings from the WHI

Tracy Madsen et al., 2020/2 PubMed #32078494 MSID: 3372
Abstract Background and Purpose- Circulating levels of SHBG (sex hormone-binding globulin) have been inversely linked to obesity, diabetes mellitus, and other cardiometabolic disorders. It remains uncertain whether low SHBG is prospectively predictive of stroke risk, particularly in women. We investigated whether SHBG is associated with risk of incident ischemic stroke (IS) among women in the WHI (Women's Health Initiative). Methods- From an observational cohort of 161 808 postmenopausal women e...
Keywords: Ischemic Stroke; Sex Hormone Binding Globulin; Sex Hormones; Prevention; Sex Differences

Relation of dietary carbohydrates intake to circulating sex hormone-binding globulin levels in postmenopausal women

Mengna Huang et al., 2017/3 PubMed #28304147 MSID: 2447
BACKGROUND: Low circulating levels of sex hormone-binding globulin (SHBG) have been shown to be a direct and strong risk factor for type 2 diabetes, cardiovascular diseases, and hormone-dependent cancers, although the relation between various aspects of dietary carbohydrates and SHBG levels remains unexplored in population studies. METHODS: Among postmenopausal women with available SHBG measurements at baseline (n = 11,159) in the Women's Health Initiative, we conducted a comprehensive assessmen...
Keywords: Dietary Carbohydrates; Glycemic Index; Glycemic Load; Sex Hormone Binding Globulin (Shbg); Type 2 Diabetes

Association of metabolomic profiles with circulating estradiol levels

Approved Proposal, Aroner, Sarah A. et al., 2016/12 MSID: 3231
Keywords: Metabolomics; Sex Steroid Hormones; Estrogen; Estradiol; Sex Hormone-Binding Globulin
Related Studies: 110, 167, BA7, BA9, BA24, W9, W10

Sex specific stroke risk score in the Women’s Health Initiative

Approved Proposal, Madsen, Tracy et al., 2020/5 MSID: 4211
Related Studies: 90, 110, 167, 238, BA7, BA9, BA21, W9, W10, W18

Correlation of endogenous sex steroid hormones with fasting glucose and insulin levels, HOMA indices, and incident diabetes mellitus in postmenopausal women

Approved Proposal, Weinstein, Amy et al., 2003/9 MSID: 266
Keywords: Diabetes; Glucose; Insulin; Endogenous Sex Steroid Hormones
Related Studies: 110

Sex hormones, sex hormones binding globulin (SHBG), and risk of ischemic stroke in men and women in WHI and TOPMed Stroke

Approved Proposal, Madsen, Tracy et al., 2020/11 MSID: 4327
Keywords: Stroke; Sex Hormone Binding Globulin; Mendelian Randomization; Single Nucleotide Polymorphisms; Ischemic Stroke
Related Studies: 90, 110, 238, BA7, BA9, BA21, W5, W9, W10, W18

Caregiving stress, stressful life events, endogenous sex steroid hormones, and breast cancer risk

Approved Manuscript, Kroenke, Candyce et al., 2012/4 MSID: 1436
Keywords: Psychosocial Stress; Caregiving; Life Events; Breast Cancer Incidence
Related Studies: 110

Serum sex hormone levels and risk of hypertension in postmenopausal women

Approved Proposal, Joffe, Hylton et al., 2003/11 MSID: 305
Keywords: Sex Steroid Hormones; Postmenopausal; Hypertension; Estrogens; Testosterone; Shbg; Estrone Sulfate; Estradiol; Dheas
Related Studies: 110

An evaluation of the effects of occupational sedentary behavior and occupational activity intensity levels on CRC risk that are mediated through presence of the metabolic syndrome and its components

Approved Proposal, Schinasi, Leah et al., 2015/11 MSID: 2828
Keywords: Occupation; Industry; Colorectal Cancer; Colon Cancer; Job Exposure Matrix; Inactivity; Sedentary Behavior; Sitting; Physical Activity; Mediation; Indirect Effects; Causal Inference; Metabolic Dysfunction; Waist Circumference
Related Studies: 83, 110, BA11, W2