This document can be used to prepare or evaluate feasibility of ancillary study proposals and paper proposals, but is NOT intended for publication.

Death Outcome Details (Form 124/120), Deaths During Consent Period Only

File NameData as ofPopulationData collectedOne row perRows
outc_death_inv.dat2/17/2024CT+OSMain, Ext1, Ext2Participant60,495
ID - WHI Participant Common ID
Col 1
NMissingMinMaxMeanStdDev
60,4950100,001299,997199,993.49857,744.198
DEATH - Death
Col 2

Did the participant die during a consented study phase?

Usage Notes:

Death was adjudicated for CT and OS participants through Ext1. In Ext2, death is only adjudicated for the Medical Record Cohort (MRC). Non MRC cause of death is determined by the initial cause of death form (form 120). See the DEATHSRC variable for details about the death adjudication process. This variable censors deaths that occur after the participant's last consented study phase, e.g. if a ppt did not consent to Ext2, but we discovered that she died during Ext2 DEATH would have a value of 0. This is done because the discovery rate of death is inconsistent after participant followup ends. See the DEATHALL variable in the All Discovered Death Outcome Detail file to see all discovered deaths.

ValueDescriptionN%
0No00
1Yes60,495100
DEATHSRC - Death ascertainment source
Col 3
Usage Notes:

During the core WHI study, central adjudications of Death were only done in the CT. In Ext1 deaths were centrally adjudicated for all participants. In Ext2, death is only adjudicated for the Medical Record Cohort (MRC). Non MRC cause of death is determined by the initial cause of death form (form 120).

ValueDescriptionN%
0Local adjudication - form 1245,3418.8
1Central adjudication - form 12418,54630.7
2National Death Index33,38755.2
10Initial report of death - form 1203,2215.3
DEATHCAUSE - Cause of Death
Col 4
Usage Notes:

"Unknown cause (Not yet adj)" (code 100) are reported deaths where the adjudication is in process. In Ext2 only MRC deaths are adjudicated. Non MRC cause of death is determined by the initial cause of death form (form 120). The cause of death values on form 120 are a subset of the causes of death that can be determined from a form 124.

If the form 124 was marked Other or Unknown cause of death the ICD code was used to determine cause of death (see the UNDRICD variable in the death detail file). A cross tabulation of DEATHCAUSE with UNDRICD should be examined to ascertain which ICD codes are included in each DEATHCAUSE category.

ValueDescriptionN%
1Breast Cancer1,7452.9
2Ovarian Cancer9501.6
3Endometrial Cancer2660.4
4Colon Cancer1,0811.8
5Rectosigmoid Cancer320.1
6Rectum Cancer1120.2
7Uterine Cancer1530.3
8Other Cancer Death5500.9
9Unknown Cancer Site6241
10Lung Cancer3,2245.3
11Definite CHD2,7774.6
12Cerebrovascular4,5827.6
13Pulmonary Embolism2990.5
14Possible CHD4,4617.4
18Other Cardiovascular6,82911.3
19Unknown Cardiovascular1250.2
21Homicide330.1
22Accident1,4502.4
23Suicide740.1
28Other Injury630.1
31Alzheimers3,3625.6
32COPD2,2473.7
33Pneumonia1,3612.2
34Pulmonary Fibrosis6531.1
35Renal Failure9781.6
36Sepsis1,2972.1
37Pancreas Cancer1,3802.3
38Lymphoma (NHL only)7451.2
39Leukemia7031.2
40Brain Cancer3910.6
41Multiple Myeloma4670.8
42Dementia NOS3,2885.4
43ALS2390.4
44Parkinson's7611.3
45Hepatic Cirrhosis2720.4
46Covid-192000.3
88Known Other Cause7,47912.4
99Unknown Cause2,1993.6
100Unknown Cause (Not yet adj)5000.8
103Accessory Sinus Cancer70
106Adrenal Gland Cancer160
109Anus Cancer300
112Appendix Cancer70
118Biliary Tract Cancer1370.2
121Bladder Cancer2860.5
124Bone-Limb Cancer50
127Bone-Non Limb Cancer180
133Central Nervous System Cancer40
136Cervix Cancer400.1
139Connective Tissue Cancer1200.2
142Endocrine Glands Cancer30
145Esophagus Cancer1590.3
148Eye and Adnexa Cancer60
151Floor Of Mouth Cancer20
154Gallbladder Cancer980.2
157Genital Organ Cancer580.1
160Gum Cancer 20
163Heart Cancer 40
166Hypopharynx Cancer10
169Kidney Cancer2680.4
172Larynx Cancer150
178Liver Cancer3110.5
181Lymph Node Cancer10
187Lymphoma, Hodgkins310.1
190Melanoma1940.3
193Meninges Cancer70
202Nasal Cavity Mid Ear Cancer30
205Nasopharynx Cancer70
208Oral (Mouth) Cancer200
211Oropharynx Cancer130
214Other Digestive Cancer350.1
220Other Lip Cancer100
223Palate Cancer40
229Parotid Gland,Stensens Cancer120
235Peritoneum Cancer1220.2
241Renal Pelvis Cancer150
244Salivary Glands Cancer30
247Small Intestine Cancer570.1
250Stomach Cancer2110.3
253Thymus Cancer 50
256Thyroid Cancer580.1
259Tongue Cancer310.1
262Tonsil Cancer30
271Ureter Cancer220
274Urinary Organs Cancer140
280Vagina Cancer220
283Vulva Cancer460.1
DEATHCAUSESRC - Cause of Death ascertainment source
Col 5
Usage Notes:

Cause of death is usually determined from the form 124 underlying cause of death subclass question. If this question is answered other/unknown and has an ICD code, the cause of death will be determined from the ICD code. In the case of an Ext2 SRC death, the cause of death comes from the form 120 subclass question.

ValueDescriptionN%
1Form 124 subclass49,33481.6
2Form 124 ICD code7,94013.1
3Form 120 subclass3,2215.3
UNDRICD - F124 ICD-9/10 CM Code
Col 6

ICD CM code relating to underlying cause of death.

Usage Notes:

These codes come directly from Form 124 – Report of Death. Early versions of form 124 recorded only ICD-9-CM codes, later versions could record ICD-9-CM or ICD-10-CM codes. The CCC reviewed some of the cases where the cause of death was “unknown” or “other” (values 8, 9, 88 or 99). In cases where a cause of death could be determined, this field has been updated with the corresponding ICD-10-CM code. Note: ICD-10-CM codes include a letter in the first position; ICD-9-CM codes do not. www.icd9data.com provides a handy reference for both version 9 and 10 ICD codes.

NMissing
47,39913,096
DTHAUTOPSY - F124 Was Autopsy Performed
Col 7

Was an autopsy performed?

Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
0No20,02033.1
1Yes8521.4
9Unknown35,85859.3
Missing3,7656.2%
DTHMEDRECS - F124 Documentation used - medical records
Col 8

Documentation used for death adjudication: Medical records documentation

Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
0No47,31578.2
1Yes9,43715.6
Missing3,7436.2%
DTHAUTOPSYREP - F124 Documentation used - autopsy findings
Col 9

Documentation used for death adjudication: Report of autopsy findings

Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
0No56,31693.1
1Yes4360.7
Missing3,7436.2%
DTHCERT - F124 Documentation used - death certificate
Col 10

Documentation used for death adjudication: Death certificate

Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
0No34,52657.1
1Yes22,22636.7
Missing3,7436.2%
DTHERREC - F124 Documentation used - ER record
Col 11

Documentation used for death adjudication:ER record

Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
0No55,99092.6
1Yes7621.3
Missing3,7436.2%
DTHEMSREP - F124 Documentation used - EMS report
Col 12

Documentation used for death adjudication: EMS report

Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
0No56,59393.5
1Yes1590.3
Missing3,7436.2%
DTHINFINT - F124 Documentation used - informant interview
Col 13

Documentation used for death adjudication: Informant interview

Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
0No55,79592.2
1Yes9571.6
Missing3,7436.2%
DTHF120 - F124 Documentation used - form 120
Col 14

Documentation used for death adjudication: Form 120 – Initial Notification of Death

Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
0No46,95777.6
1Yes9,79516.2
Missing3,7436.2%
DTHNDISRCH - F124 Documentation used - NDI search
Col 15

Documentation used for death adjudication: National Death Index search

Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
0No23,30838.5
1Yes33,44455.3
Missing3,7436.2%
DTHCORREP - F124 Documentation used - coroners report
Col 16

Documentation used for death adjudication: Coroner’s report

Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
0No56,69293.7
1Yes600.1
Missing3,7436.2%
DTHOTHERDOC - F124 Documentation used - other
Col 17

Documentation used for death adjudication: Other

Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
0No51,96985.9
1Yes4,7837.9
Missing3,7436.2%
DTHMI - F124 Coronary Death MI
Col 18

Coronary death based on: Hospitalized myocardial infarction within 28 days of death

Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
0No6,54510.8
1Yes5360.9
Missing53,41488.3%
DTHPREVANGINA - F124 Coronary Death prev Angina, MI or Revasc
Col 19

Coronary death based on: Previous angina, myocardial infarction, or revascularization procedure and no known potentially lethal non-coronary disease process

Usage Notes:

Not on early versions of form 124. Revascularizations added after WHI closeout.

ValueDescriptionN%
0No6,20810.3
1Yes8731.4
Missing53,41488.3%
DTHCHD - F124 Coronary death CHD
Col 20

Coronary death based on: Coronary heart disease (CHD) diagnosed as cause of death at post-mortem examination

Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
0No6,94211.5
1Yes1390.2
Missing53,41488.3%
DTHCABGPTCA - F124 Coronary Death CABG/PTCA
Col 21

Coronary death based on: Death resulting from a CHD-related procedure, such as coronary bypass grafting (CABG) or percutaneous transluminal coronary angioplasty (PTCA)

Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
0No6,98411.5
1Yes970.2
Missing53,41488.3%
DTHOTHER - F124 Coronary death other
Col 22

Coronary death based on: Other (none of the above)

Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
0No1,4722.4
1Yes5,6099.3
Missing53,41488.3%
DTHCORSUBCLASS - F124 Coronary Subclass
Col 23

Coronary death subclassification:

Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
1Definite fatal MI5400.9
2Definite fatal CHD8241.4
3Possible fatal CHD5,7189.5
Missing53,41388.3%
DTHCORTIMING - F124 Coronary Death Timing
Col 24
Usage Notes:

Not on early versions of form 124

ValueDescriptionN%
1Sudden death w/in one hr5931
2Rapid death w/in 1 - 24 hrs3990.7
3Other coronary death (not sudden/rapid)6,08210.1
Missing53,42188.3%