This document can be used to prepare or evaluate feasibility of ancillary study proposals and paper proposals, but is NOT intended for publication.

WHI Long Life Study 2 Visits All

File Name	Data as of	Population	Data collected	One row per	Rows
f301_whills2_all_inv.dat	2/15/2025	WHI-LLS2	WHI-LLS2		5,905

This file contains all visits from the Long Life Study 2 including those that were funded by the LILAC study and were not included in the ""WHI Long Life Study 2 Visits"" Investigator release file. Form 301 Supplemental Documentation: * Long Life Study Short Physical Performance Battery (SPPB) Scoring

ID - WHI Participant Common ID

Col 1

N	Missing
5,905	0

FUNDSRC - Exam funding source

Col 2

Value	Description	N	%
1	WHI	3,905	66.1
2	LILAC	2,000	33.9

PPTDRW - Participant Draw Number

Col 3

ID and PPTDRW identify a specimen draw.

Usage Notes:

Use ID and PPTDRW to merge with the specimen draws file (spec_draws) or the specimen results file (spec_results).

N	Missing	Min	Max	Mean	StdDev
5,512	393	2	14	3.925	1.343

F301DY - F301 Days since randomization or enrollment

Col 4

Usage Notes:

Is the day the Long Life Study 2 exam was performed

N	Missing	Min	Max	Mean	StdDev
5,905	0	8,800	11,047	9,842.507	420.551

F301VTYP - Visit Type

Col 5

Value	Description	N	%
4	Non-Routine visit	5,905	100

F301VY - Visit Year

Col 6

Visit year for which this form was collected.

N	Missing	Min	Max	Mean	StdDev
5,905	0	24	30	27.197	1.19

EXAMTIME24 - Exam Time 24

Col 7

Computed variable: Time the exam was performed in 24 hour time. Format HH24:MI.

N	Missing
5,893	12

EXAMLOC - Exam location

Col 8

Value	Description	N	%
4	Participant's Home	5,855	99.2
8	Other Location	30	0.5
	Missing	20	0.3%

REVISITEXAM - Participant had a revisit

Col 9

Revisit performed to collect or correct data.

Value	Description	N	%
0	No	5,842	98.9
1	Yes	63	1.1

REVISITF301DY - Revisit F301 Days since randomization or enrollment

Col 10

Usage Notes:

Is the day the Long Life Study 2 revisit exam was performed

N	Missing	Min	Max	Mean	StdDev
63	5,842	9,075	11,066	9,907.81	528.159

REVISITF301VY - Revisit Visit Year

Col 11

Visit year for which this form was collected.

N	Missing	Min	Max	Mean	StdDev
63	5,842	25	31	27.413	1.499

REVISITEXAMTIME24 - Revisit exam time 24

Col 12

Computed variable: Time the exam was performed in 24 hour time. Format HH24:MI.

N	Missing
62	5,843

REVISITEXAMLOC - Revisit exam location

Col 13

Value	Description	N	%
4	Participant's Home	63	1.1
8	Other Location	0	0
	Missing	5,842	98.9%

REVISITPULSEBP - Revisit Pulse and BP

Col 14

Usage Notes:

Pulse and BP values (PULSE60, SYSTBP1, DIASBP1, SYSTBP2, DIASBP2) measured during participant revisit.

Value	Description	N	%
0	No	5,795	98.1
1	Yes	36	0.6
	Missing	74	1.3%

PULSE60 - Resting pulse in 60 seconds

Col 15

N	Missing	Min	Max	Mean	StdDev
5,823	82	34	139	69.657	9.848

SYSTBP1 - Systolic blood pressure (1st reading)

Col 16

N	Missing	Min	Max	Mean	StdDev
5,830	75	80	219	129.11	16.442

DIASBP1 - Diastolic blood pressure (1st reading)

Col 17

N	Missing	Min	Max	Mean	StdDev
5,823	82	40	120	73.322	9.412

SYSTBP2 - Systolic blood pressure (2nd reading)

Col 18

N	Missing	Min	Max	Mean	StdDev
5,817	88	80	212	127.214	15.607

DIASBP2 - Diastolic blood pressure (2nd reading)

Col 19

N	Missing	Min	Max	Mean	StdDev
5,829	76	40	119	72.332	9.18

REVISITGRIP - Revisit Grip

Col 20

Usage Notes:

Grip performance measures (DYNASET, GRIPCOMP, GRIPDOM, RGRIPSTR1, RGRIPSTR2, LGRIPSTR1, LGRIPSTR2) measured during participant revisit.

Value	Description	N	%
0	No	5,751	97.4
1	Yes	41	0.7
	Missing	113	1.9%

DYNASET - Dynamometer setting

Col 21

N	Missing	Min	Max	Mean	StdDev
3,743	2,162	1	4	1.982	0.199

GRIPCOMP - Grip strength: completion

Col 22

Value	Description	N	%
1	Test completed on one or both	5,583	94.5
2	Attempted, unable to complete on either side	35	0.6
8	Refused	3	0.1
10	Not attempted because dynamometer not available	1	0
11	Participant refused to continue with visit	0	0
	Missing	283	4.8%

GRIPDOM - Grip strength: Dominant hand

Col 23

Value	Description	N	%
1	Right	5,187	87.8
2	Left	431	7.3
3	Don't know	17	0.3
	Missing	270	4.6%

RGRIPSTR1 - Right grip strength measurement 1 (kg)

Col 24

Right hand grip strength: Measurement #1 (kg).

N	Missing	Min	Max	Mean	StdDev
5,600	305	0	60	13.657	6.109

RGRIPSTR2 - Right grip strength measurement 2 (kg)

Col 25

Right hand grip strength: Measurement #2 (kg).

N	Missing	Min	Max	Mean	StdDev
5,583	322	0	60	13.707	6.174

LGRIPSTR1 - Left grip strength measurement 1 (kg)

Col 26

Left hand grip strength: Measurement #1 (kg).

N	Missing	Min	Max	Mean	StdDev
5,580	325	0	50	12.27	5.992

LGRIPSTR2 - Left grip strength measurement 2 (kg)

Col 27

Left hand grip strength: Measurement #2 (kg).

N	Missing	Min	Max	Mean	StdDev
5,561	344	0	60	12.292	5.949

VISCOMP - Vision screening completion

Col 28

Usage Notes:

The vision screening assessment was only included on version 5 of Form 301, so a large number of participants did not have the screening.

Value	Description	N	%
0	No	28	0.5
1	Yes	3,699	62.6
	Missing	2,178	36.9%

NOVIS - No vision screening reason

Col 29

Value	Description	N	%
1	Participant declined vision screening	7	0.1
2	Participant could not complete the screening	9	0.2
3	Phone did not work	6	0.1
4	Other	24	0.4
	Missing	5,859	99.2%

DRAWSUCCESS - Specimen draw success flag

Col 30

Flag indicating that the specimen collection in the exam was successful.

Usage Notes:

Value	Description	N	%
0	No	393	6.7
1	Yes	5,512	93.3

NODRAW - No draw reason

Col 31

Usage Notes:

Value	Description	N	%
1	Participant declined	159	2.7
2	Participant too apprehensive	4	0.1
3	Found no acceptable veins for a draw attempt	9	0.2
4	Participant refused to complete the visit	1	0
5	Visit ended due to health and safety reasons	0	0
8	Other	5	0.1
	Missing	5,727	97%

REVISITANTHRO - Revisit Anthropometrics

Col 32

Usage Notes:

Anthropomorphic measures (KYPHOSIS, HEIGHT, WEIGHT, OVER400LBS, WAIST, ANTHROCOMP) measured during participant revisit.

Value	Description	N	%
0	No	5,795	98.1
1	Yes	36	0.6
	Missing	74	1.3%

KYPHOSIS - Kyphosis Assessment

Col 33

N	Missing	Min	Max	Mean	StdDev
5,548	357	0	3	0.889	0.774

HEIGHT - Height, in

Col 34

N	Missing	Min	Max	Mean	StdDev
5,460	445	47	86	62.603	3.042

WEIGHT - Weight, lb

Col 35

N	Missing	Min	Max	Mean	StdDev
5,481	424	80	342	150.713	31.27

OVER400LBS - Self-report, participant exceeds 400 lbs

Col 36

Value	Description	N	%
0	No	0	0
1	Yes	17	0.3
	Missing	5,888	99.7%

WAIST - Waist circumference, in

Col 37

N	Missing	Min	Max	Mean	StdDev
5,468	437	20	70	35.827	5.369

ANTHROCOMP - Anthropometrics completion

Col 38

Value	Description	N	%
1	Measurements completed	5,482	92.8
2	Attempted, unable to complete for safety reasons	26	0.4
4	Unable to continue with visit due to health and safety concerns	12	0.2
5	Refused to continue with visit	2	0
	Missing	383	6.5%

REVISITBALANCE - Revisit Balance tests

Col 39

Usage Notes:

Balance tests (SBSCOMP, SBSTIME, SEMITDMCOMP, SEMITDMTIME, TDMCOMP, TDMTIME1, TDMTIME2, ONELEGCOMP, ONELEGTIME1, ONELEGTIME2, NOBLNCRSN, BLNCMETH) measured during participant revisit.

Value	Description	N	%
0	No	5,682	96.2
1	Yes	63	1.1
	Missing	160	2.7%

SBSCOMP - Side by side: completion

Col 40

Side-by-side balance test completed.

Value	Description	N	%
0	No	63	1.1
1	Yes	4,864	82.4
	Missing	978	16.6%

SBSTIME - Side by side: time

Col 41

Side-by-side balance test time (seconds).

Usage Notes:

Test designed as a screen for all following balance tests. Maximum possible time set to 10 seconds.

N	Missing	Min	Max	Mean	StdDev
4,862	1,043	0.08	10	9.784	1.028

SEMITDMCOMP - Semi tandem: completion

Col 42

Semi-tandem balance test completed.

Usage Notes:

Test designed to be completed only if SBSTIME >= 10.0 seconds.

Value	Description	N	%
0	No	239	4
1	Yes	4,317	73.1
	Missing	1,349	22.8%

SEMITDMTIME - Semi tandem: time

Col 43

Semi-tandem balance test time (seconds).

Usage Notes:

Test designed to be completed only if SBSTIME >= 10.0 seconds. Maximum possible time set to 30 seconds.

N	Missing	Min	Max	Mean	StdDev
4,305	1,600	0.01	30	27.851	6.185

TDMCOMP - Tandem stand: completion

Col 44

Tandem stand balance test completed.

Usage Notes:

Test designed to be completed only if SEMITDMTIME >= 30.0 seconds.

Value	Description	N	%
0	No	662	11.2
1	Yes	3,062	51.9
	Missing	2,181	36.9%

TDMTIME1 - Tandem stand: time 1

Col 45

Tandem stand balance test time #1 (seconds).

Usage Notes:

Test designed to be completed only if SEMITDMTIME >= 30.0 seconds. Maximum possible time set to 30 seconds.

N	Missing	Min	Max	Mean	StdDev
3,048	2,857	0.35	30	24.5	9.552

TDMTIME2 - Tandem stand: time 2

Col 46

Tandem stand balance test time #2 (seconds).

Usage Notes:

Second try allowed if TDMTIME1 < 30.0 seconds. Maximum possible time set to 30 seconds.

N	Missing	Min	Max	Mean	StdDev
782	5,123	0.75	30	13.849	10.044

ONELEGCOMP - One leg: completion

Col 47

One leg balance test completion.

Usage Notes:

Test designed to be completed only if one of the TDMTIMEs >= 30.0 seconds.

Value	Description	N	%
0	No	758	12.8
1	Yes	1,544	26.1
	Missing	3,603	61%

ONELEGTIME1 - One leg: time 1

Col 48

One leg balance test time #1 (seconds).

Usage Notes:

Test designed to be completed only if one of the TDMTIMEs >= 30.0 seconds. Maximum possible time set to 30 seconds.

N	Missing	Min	Max	Mean	StdDev
1,540	4,365	0.01	30	18.345	11.19

ONELEGTIME2 - One leg: time 2

Col 49

One leg balance test time #2 (seconds).

Usage Notes:

Second try allowed if ONELEGTIME1 < 30.0 seconds. Maximum possible time set to 30 seconds.

N	Missing	Min	Max	Mean	StdDev
821	5,084	0.02	30	11.403	8.702

NOBLNCRSN - No balance test reason

Col 50

Usage Notes:

Item associated with the first balance test not attempted or completed

Value	Description	N	%
1	Refused	68	1.2
2	Not safe	285	4.8
3	Tried, but unable	1,354	22.9
4	Participant confined to wheelchair	0	0
5	Participant refused to complete the visit	10	0.2
	Missing	4,188	70.9%

BLNCMETH - Balance test timing method

Col 51

Value	Description	N	%
1	Stop watch	4,507	76.3
8	Other	291	4.9
	Missing	1,107	18.7%

REVISITTMDWLK - Revisit Timed walk

Col 52

Usage Notes:

Timed walk (FLRTYP, FLRSPACE, COURSLEN, TMDWALKCOMP, ASSTDVC, TMDWALKTIME1, STEPS1, ADDLSTEPS1, STEPSBEYOND1, TMDWALKTIME2, STEPS2, ADDLSTEPS2, STEPSBEYOND2) measured during participant revisit.

Value	Description	N	%
0	No	5,751	97.4
1	Yes	41	0.7
	Missing	113	1.9%

FLRTYP - Floor type

Col 53

Floor type for timed walk.

Value	Description	N	%
1	Bare floors	3,676	62.3
2	Carpet or mixed flooring	1,424	24.1
3	Unsafe flooring (Do not perform test)	379	6.4
	Missing	426	7.2%

FLRSPACE - Floor space

Col 54

Value	Description	N	%
1	There is sufficient space	4,917	83.3
2	Not attempted because insufficient space available	180	3
	Missing	808	13.7%

COURSLEN - Course length

Col 55

Course length for timed walk.

Value	Description	N	%
1	4 meters	2,822	47.8
2	3 meters	2,007	34
	Missing	1,076	18.2%

TMDWALKCOMP - Timed walk: completion

Col 56

Value	Description	N	%
1	Test completed	4,820	81.6
2	Attempted, unable to complete	12	0.2
8	Refused	0	0
13	Participant refused to continue with visit	0	0
	Missing	1,073	18.2%

ASSTDVC - Assistive device used

Col 57

Assistive device used for timed walk.

Usage Notes:

Value	Description	N	%
0	No	4,306	72.9
1	Yes	509	8.6
	Missing	1,090	18.5%

TMDWALKTIME1 - Timed walk: time 1

Col 58

Timed walk test time #1 (seconds).

Usage Notes:

N	Missing	Min	Max	Mean	StdDev
4,818	1,087	2	120	8.178	7.242

STEPS1 - Step count (1st attempt)

Col 59

N	Missing	Min	Max	Mean	StdDev
4,822	1,083	2	110	9.86	4.783

ADDLSTEPS1 - Participant took steps beyond the end (1st attempt)

Col 60

Value	Description	N	%
0	No	4,239	71.8
1	Yes	566	9.6
	Missing	1,100	18.6%

STEPSBEYOND1 - Steps beyond finish (1st attempt)

Col 61

N	Missing	Min	Max	Mean	StdDev
565	5,340	0	14	2.466	2.558

TMDWALKTIME2 - Timed walk: time 2

Col 62

Timed walk test time #2 (seconds).

Usage Notes:

N	Missing	Min	Max	Mean	StdDev
4,782	1,123	2	119	7.661	6.427

STEPS2 - Step count (2nd attempt)

Col 63

N	Missing	Min	Max	Mean	StdDev
4,772	1,133	0	88	9.528	4.445

ADDLSTEPS2 - Participant took steps beyond the end (2nd attempt)

Col 64

Value	Description	N	%
0	No	4,122	69.8
1	Yes	572	9.7
	Missing	1,211	20.5%

STEPSBEYOND2 - Steps beyond finish (2nd attempt)

Col 65

N	Missing	Min	Max	Mean	StdDev
570	5,335	0	25	2.565	2.958

REVISITCHR - Revisit Chair stand

Col 66

Usage Notes:

Chair stand (CHAIRTYP, SNGCHRSTNDCOMP, RPTCHRSTNDCOMP, RPTCHRTIME, REVISITCHR) measured during participant revisit.

Value	Description	N	%
0	No	5,751	97.4
1	Yes	41	0.7
	Missing	113	1.9%

CHAIRTYP - Chair type

Col 67

Chair type for chair stand.

Value	Description	N	%
1	Per protocol	4,484	75.9
2	Not per protocol, but acceptable	268	4.5
3	Not per protocol	63	1.1
	Missing	1,090	18.5%

SNGCHRSTNDCOMP - Single chair stand: completion

Col 68

Value	Description	N	%
1	Test completed	4,559	77.2
2	Participant tried, but unable to complete	179	3
8	Refused	4	0.1
9	Not attempted for safety or health reasons	10	0.2
	Missing	1,153	19.5%

RPTCHRSTNDCOMP - Repeated chair stand: completion

Col 69

Value	Description	N	%
1	Test completed	4,454	75.4
2	Participant tried, but unable to complete	89	1.5
8	Refused	4	0.1
9	Not attempted for safety or health reasons	11	0.2
	Missing	1,347	22.8%

RPTCHRTIME - Repeated chair stand: time

Col 70

Repeated chair stand: time it took to rise out of a chair 5 times in succession (seconds).

Usage Notes:

Maximum possible time set to 60 seconds.

N	Missing	Min	Max	Mean	StdDev
4,393	1,512	4	60	16.549	9.251

BMI - Body-mass Index (BMI), kg/m2

Col 71

If a participant's BMI is greater than 70, BMI is missing.

N	Missing	Min	Max	Mean	StdDev
5,439	466	13.718	57.365	27.08	5.59

BMIC - Body-mass Index (BMI), kg/m2

Col 72

Computed from Form 301, height and weight. Reference: Expert Panel on the identification, evaluation, and treatment on overweight in adults (1998). Categorization of BMI into six groups. If a participant's BMI is greater than 70, BMIC is missing.

Value	Description	N	%
1	Underweight (< 18.5)	135	2.3
2	Normal (18.5 - 24.9)	2,013	34.1
3	Overweight (25.0 - 29.9)	1,930	32.7
4	Obesity I (30.0 - 34.9)	897	15.2
5	Obesity II (35.0 - 39.9)	312	5.3
6	Extreme Obesity III (>= 40)	152	2.6
	Missing	466	7.9%

LASPPB - Look AHEAD short physical performance battery score

Col 73

A continuous score (0-3) calculated as the sum of balance, chair stand, and gait speed ratios. See data prep document for details.

Usage Notes:

N	Missing	Min	Max	Mean	StdDev
3,950	1,955	0	3	1.564	0.523

EPESESPPB - EPESE short physical performance battery score

Col 74

A continuous score (0-12) calculated as the sum of balance, chair stand, and gait speed scores. See data prep document for details.

Usage Notes:

N	Missing	Min	Max	Mean	StdDev
4,264	1,641	0	12	7.509	2.646