This document can be used to prepare or evaluate feasibility of ancillary study proposals and paper proposals, but is NOT intended for publication.

WHI Long Life Study 2 Visits

File Name	Data as of	Population	Data collected	One row per	Rows
f301_whills2_inv.dat	2/15/2025	WHI-LLS2	WHI-LLS2		3,905

The WHI Long Life Study 2 (WHILLS2) visits for 2000 LILAC participants were funded by LILAC; access to the WHILLS2 Form 301 and biospecimen data for these participants currently requires approval from the LILAC PIs. WHILLS2 Form 301 and biospecimen data for the 3905 WHILLS2 visits not funded by LILAC is available through the WHI data repository. To request approval for access to WHILLS2 F301 and/or biospecimen data for the additional 2000 LILAC-funded participants, please contact the WHI Help Desk (helpdesk@whi.org) with your specific request. Form 301 Supplemental Documentation: * Long Life Study Short Physical Performance Battery (SPPB) Scoring

ID - WHI Participant Common ID

Col 1

N	Missing
3,905	0

FUNDSRC - Exam funding source

Col 2

Value	Description	N	%
1	WHI	3,905	100
2	LILAC	0	0

PPTDRW - Participant Draw Number

Col 3

ID and PPTDRW identify a specimen draw.

Usage Notes:

Use ID and PPTDRW to merge with the specimen draws file (spec_draws) or the specimen results file (spec_results).

N	Missing	Min	Max	Mean	StdDev
3,656	249	2	14	4.107	1.434

F301DY - F301 Days since randomization or enrollment

Col 4

Usage Notes:

Is the day the Long Life Study 2 exam was performed

N	Missing	Min	Max	Mean	StdDev
3,905	0	8,800	11,047	9,807.608	422.498

F301VTYP - Visit Type

Col 5

Value	Description	N	%
4	Non-Routine visit	3,905	100

F301VY - Visit Year

Col 6

Visit year for which this form was collected.

N	Missing	Min	Max	Mean	StdDev
3,905	0	24	30	27.1	1.197

EXAMTIME24 - Exam Time 24

Col 7

Computed variable: Time the exam was performed in 24 hour time. Format HH24:MI.

N	Missing
3,896	9

EXAMLOC - Exam location

Col 8

Value	Description	N	%
4	Participant's Home	3,867	99
8	Other Location	25	0.6
	Missing	13	0.3%

REVISITEXAM - Participant had a revisit

Col 9

Revisit performed to collect or correct data.

Value	Description	N	%
0	No	3,858	98.8
1	Yes	47	1.2

REVISITF301DY - Revisit F301 Days since randomization or enrollment

Col 10

Usage Notes:

Is the day the Long Life Study 2 revisit exam was performed

N	Missing	Min	Max	Mean	StdDev
47	3,858	9,075	11,066	9,982.064	552.713

REVISITF301VY - Revisit Visit Year

Col 11

Visit year for which this form was collected.

N	Missing	Min	Max	Mean	StdDev
47	3,858	25	31	27.617	1.568

REVISITEXAMTIME24 - Revisit exam time 24

Col 12

Computed variable: Time the exam was performed in 24 hour time. Format HH24:MI.

N	Missing
46	3,859

REVISITEXAMLOC - Revisit exam location

Col 13

Value	Description	N	%
4	Participant's Home	47	1.2
8	Other Location	0	0
	Missing	3,858	98.8%

REVISITPULSEBP - Revisit Pulse and BP

Col 14

Usage Notes:

Pulse and BP values (PULSE60, SYSTBP1, DIASBP1, SYSTBP2, DIASBP2) measured during participant revisit.

Value	Description	N	%
0	No	3,825	98
1	Yes	32	0.8
	Missing	48	1.2%

PULSE60 - Resting pulse in 60 seconds

Col 15

N	Missing	Min	Max	Mean	StdDev
3,852	53	39	139	69.591	9.931

SYSTBP1 - Systolic blood pressure (1st reading)

Col 16

N	Missing	Min	Max	Mean	StdDev
3,857	48	80	219	129.477	16.612

DIASBP1 - Diastolic blood pressure (1st reading)

Col 17

N	Missing	Min	Max	Mean	StdDev
3,850	55	40	120	73.347	9.462

SYSTBP2 - Systolic blood pressure (2nd reading)

Col 18

N	Missing	Min	Max	Mean	StdDev
3,846	59	80	212	127.619	15.738

DIASBP2 - Diastolic blood pressure (2nd reading)

Col 19

N	Missing	Min	Max	Mean	StdDev
3,856	49	40	119	72.328	9.193

REVISITGRIP - Revisit Grip

Col 20

Usage Notes:

Grip performance measures (DYNASET, GRIPCOMP, GRIPDOM, RGRIPSTR1, RGRIPSTR2, LGRIPSTR1, LGRIPSTR2) measured during participant revisit.

Value	Description	N	%
0	No	3,797	97.2
1	Yes	33	0.8
	Missing	75	1.9%

DYNASET - Dynamometer setting

Col 21

N	Missing	Min	Max	Mean	StdDev
2,264	1,641	1	4	1.978	0.199

GRIPCOMP - Grip strength: completion

Col 22

Value	Description	N	%
1	Test completed on one or both	3,693	94.6
2	Attempted, unable to complete on either side	19	0.5
8	Refused	2	0.1
10	Not attempted because dynamometer not available	1	0
11	Participant refused to continue with visit	0	0
	Missing	190	4.9%

GRIPDOM - Grip strength: Dominant hand

Col 23

Value	Description	N	%
1	Right	3,424	87.7
2	Left	284	7.3
3	Don't know	14	0.4
	Missing	183	4.7%

RGRIPSTR1 - Right grip strength measurement 1 (kg)

Col 24

Right hand grip strength: Measurement #1 (kg).

N	Missing	Min	Max	Mean	StdDev
3,699	206	0	60	13.77	6.186

RGRIPSTR2 - Right grip strength measurement 2 (kg)

Col 25

Right hand grip strength: Measurement #2 (kg).

N	Missing	Min	Max	Mean	StdDev
3,683	222	0	55	13.837	6.234

LGRIPSTR1 - Left grip strength measurement 1 (kg)

Col 26

Left hand grip strength: Measurement #1 (kg).

N	Missing	Min	Max	Mean	StdDev
3,685	220	0	42	12.424	6.104

LGRIPSTR2 - Left grip strength measurement 2 (kg)

Col 27

Left hand grip strength: Measurement #2 (kg).

N	Missing	Min	Max	Mean	StdDev
3,669	236	0	42	12.467	6.023

VISCOMP - Vision screening completion

Col 28

Usage Notes:

The vision screening assessment was only included on version 5 of Form 301, so a large number of participants did not have the screening.

Value	Description	N	%
0	No	17	0.4
1	Yes	2,214	56.7
	Missing	1,674	42.9%

NOVIS - No vision screening reason

Col 29

Value	Description	N	%
1	Participant declined vision screening	2	0.1
2	Participant could not complete the screening	5	0.1
3	Phone did not work	5	0.1
4	Other	14	0.4
	Missing	3,879	99.3%

DRAWSUCCESS - Specimen draw success flag

Col 30

Flag indicating that the specimen collection in the exam was successful.

Usage Notes:

Value	Description	N	%
0	No	249	6.4
1	Yes	3,656	93.6

NODRAW - No draw reason

Col 31

Usage Notes:

Value	Description	N	%
1	Participant declined	103	2.6
2	Participant too apprehensive	1	0
3	Found no acceptable veins for a draw attempt	8	0.2
4	Participant refused to complete the visit	0	0
5	Visit ended due to health and safety reasons	0	0
8	Other	4	0.1
	Missing	3,789	97%

REVISITANTHRO - Revisit Anthropometrics

Col 32

Usage Notes:

Anthropomorphic measures (KYPHOSIS, HEIGHT, WEIGHT, OVER400LBS, WAIST, ANTHROCOMP) measured during participant revisit.

Value	Description	N	%
0	No	3,825	98
1	Yes	32	0.8
	Missing	48	1.2%

KYPHOSIS - Kyphosis Assessment

Col 33

N	Missing	Min	Max	Mean	StdDev
3,655	250	0	3	0.879	0.774

HEIGHT - Height, in

Col 34

N	Missing	Min	Max	Mean	StdDev
3,599	306	47	86	62.487	3.008

WEIGHT - Weight, lb

Col 35

N	Missing	Min	Max	Mean	StdDev
3,613	292	80	342	152.312	31.882

OVER400LBS - Self-report, participant exceeds 400 lbs

Col 36

Value	Description	N	%
0	No	0	0
1	Yes	11	0.3
	Missing	3,894	99.7%

WAIST - Waist circumference, in

Col 37

N	Missing	Min	Max	Mean	StdDev
3,601	304	20	70	36.083	5.5

ANTHROCOMP - Anthropometrics completion

Col 38

Value	Description	N	%
1	Measurements completed	3,615	92.6
2	Attempted, unable to complete for safety reasons	14	0.4
4	Unable to continue with visit due to health and safety concerns	7	0.2
5	Refused to continue with visit	1	0
	Missing	268	6.9%

REVISITBALANCE - Revisit Balance tests

Col 39

Usage Notes:

Balance tests (SBSCOMP, SBSTIME, SEMITDMCOMP, SEMITDMTIME, TDMCOMP, TDMTIME1, TDMTIME2, ONELEGCOMP, ONELEGTIME1, ONELEGTIME2, NOBLNCRSN, BLNCMETH) measured during participant revisit.

Value	Description	N	%
0	No	3,747	96
1	Yes	47	1.2
	Missing	111	2.8%

SBSCOMP - Side by side: completion

Col 40

Side-by-side balance test completed.

Value	Description	N	%
0	No	43	1.1
1	Yes	3,176	81.3
	Missing	686	17.6%

SBSTIME - Side by side: time

Col 41

Side-by-side balance test time (seconds).

Usage Notes:

Test designed as a screen for all following balance tests. Maximum possible time set to 10 seconds.

N	Missing	Min	Max	Mean	StdDev
3,174	731	0.08	10	9.744	1.12

SEMITDMCOMP - Semi tandem: completion

Col 42

Semi-tandem balance test completed.

Usage Notes:

Test designed to be completed only if SBSTIME >= 10.0 seconds.

Value	Description	N	%
0	No	168	4.3
1	Yes	2,771	71
	Missing	966	24.7%

SEMITDMTIME - Semi tandem: time

Col 43

Semi-tandem balance test time (seconds).

Usage Notes:

Test designed to be completed only if SBSTIME >= 10.0 seconds. Maximum possible time set to 30 seconds.

N	Missing	Min	Max	Mean	StdDev
2,760	1,145	0.01	30	27.883	6.054

TDMCOMP - Tandem stand: completion

Col 44

Tandem stand balance test completed.

Usage Notes:

Test designed to be completed only if SEMITDMTIME >= 30.0 seconds.

Value	Description	N	%
0	No	418	10.7
1	Yes	1,962	50.2
	Missing	1,525	39.1%

TDMTIME1 - Tandem stand: time 1

Col 45

Tandem stand balance test time #1 (seconds).

Usage Notes:

Test designed to be completed only if SEMITDMTIME >= 30.0 seconds. Maximum possible time set to 30 seconds.

N	Missing	Min	Max	Mean	StdDev
1,948	1,957	0.35	30	24.23	9.701

TDMTIME2 - Tandem stand: time 2

Col 46

Tandem stand balance test time #2 (seconds).

Usage Notes:

Second try allowed if TDMTIME1 < 30.0 seconds. Maximum possible time set to 30 seconds.

N	Missing	Min	Max	Mean	StdDev
521	3,384	0.75	30	13.892	10.133

ONELEGCOMP - One leg: completion

Col 47

One leg balance test completion.

Usage Notes:

Test designed to be completed only if one of the TDMTIMEs >= 30.0 seconds.

Value	Description	N	%
0	No	481	12.3
1	Yes	976	25
	Missing	2,448	62.7%

ONELEGTIME1 - One leg: time 1

Col 48

One leg balance test time #1 (seconds).

Usage Notes:

Test designed to be completed only if one of the TDMTIMEs >= 30.0 seconds. Maximum possible time set to 30 seconds.

N	Missing	Min	Max	Mean	StdDev
973	2,932	0.01	30	17.923	11.27

ONELEGTIME2 - One leg: time 2

Col 49

One leg balance test time #2 (seconds).

Usage Notes:

Second try allowed if ONELEGTIME1 < 30.0 seconds. Maximum possible time set to 30 seconds.

N	Missing	Min	Max	Mean	StdDev
525	3,380	0.02	30	11.152	8.604

NOBLNCRSN - No balance test reason

Col 50

Usage Notes:

Item associated with the first balance test not attempted or completed

Value	Description	N	%
1	Refused	46	1.2
2	Not safe	187	4.8
3	Tried, but unable	870	22.3
4	Participant confined to wheelchair	0	0
5	Participant refused to complete the visit	5	0.1
	Missing	2,797	71.6%

BLNCMETH - Balance test timing method

Col 51

Value	Description	N	%
1	Stop watch	2,982	76.4
8	Other	164	4.2
	Missing	759	19.4%

REVISITTMDWLK - Revisit Timed walk

Col 52

Usage Notes:

Timed walk (FLRTYP, FLRSPACE, COURSLEN, TMDWALKCOMP, ASSTDVC, TMDWALKTIME1, STEPS1, ADDLSTEPS1, STEPSBEYOND1, TMDWALKTIME2, STEPS2, ADDLSTEPS2, STEPSBEYOND2) measured during participant revisit.

Value	Description	N	%
0	No	3,797	97.2
1	Yes	33	0.8
	Missing	75	1.9%

FLRTYP - Floor type

Col 53

Floor type for timed walk.

Value	Description	N	%
1	Bare floors	2,396	61.4
2	Carpet or mixed flooring	926	23.7
3	Unsafe flooring (Do not perform test)	288	7.4
	Missing	295	7.6%

FLRSPACE - Floor space

Col 54

Value	Description	N	%
1	There is sufficient space	3,190	81.7
2	Not attempted because insufficient space available	129	3.3
	Missing	586	15%

COURSLEN - Course length

Col 55

Course length for timed walk.

Value	Description	N	%
1	4 meters	1,798	46
2	3 meters	1,332	34.1
	Missing	775	19.8%

TMDWALKCOMP - Timed walk: completion

Col 56

Value	Description	N	%
1	Test completed	3,125	80
2	Attempted, unable to complete	7	0.2
8	Refused	0	0
13	Participant refused to continue with visit	0	0
	Missing	773	19.8%

ASSTDVC - Assistive device used

Col 57

Assistive device used for timed walk.

Usage Notes:

Value	Description	N	%
0	No	2,788	71.4
1	Yes	334	8.6
	Missing	783	20.1%

TMDWALKTIME1 - Timed walk: time 1

Col 58

Timed walk test time #1 (seconds).

Usage Notes:

N	Missing	Min	Max	Mean	StdDev
3,123	782	2.2	120	8.553	7.998

STEPS1 - Step count (1st attempt)

Col 59

N	Missing	Min	Max	Mean	StdDev
3,125	780	2	110	10.037	4.872

ADDLSTEPS1 - Participant took steps beyond the end (1st attempt)

Col 60

Value	Description	N	%
0	No	2,740	70.2
1	Yes	378	9.7
	Missing	787	20.2%

STEPSBEYOND1 - Steps beyond finish (1st attempt)

Col 61

N	Missing	Min	Max	Mean	StdDev
378	3,527	1	12	2.644	2.707

TMDWALKTIME2 - Timed walk: time 2

Col 62

Timed walk test time #2 (seconds).

Usage Notes:

N	Missing	Min	Max	Mean	StdDev
3,093	812	2	119	7.978	7.028

STEPS2 - Step count (2nd attempt)

Col 63

N	Missing	Min	Max	Mean	StdDev
3,083	822	2	88	9.712	4.484

ADDLSTEPS2 - Participant took steps beyond the end (2nd attempt)

Col 64

Value	Description	N	%
0	No	2,666	68.3
1	Yes	377	9.7
	Missing	862	22.1%

STEPSBEYOND2 - Steps beyond finish (2nd attempt)

Col 65

N	Missing	Min	Max	Mean	StdDev
375	3,530	0	25	2.864	3.257

REVISITCHR - Revisit Chair stand

Col 66

Usage Notes:

Chair stand (CHAIRTYP, SNGCHRSTNDCOMP, RPTCHRSTNDCOMP, RPTCHRTIME, REVISITCHR) measured during participant revisit.

Value	Description	N	%
0	No	3,797	97.2
1	Yes	33	0.8
	Missing	75	1.9%

CHAIRTYP - Chair type

Col 67

Chair type for chair stand.

Value	Description	N	%
1	Per protocol	2,951	75.6
2	Not per protocol, but acceptable	172	4.4
3	Not per protocol	48	1.2
	Missing	734	18.8%

SNGCHRSTNDCOMP - Single chair stand: completion

Col 68

Value	Description	N	%
1	Test completed	2,982	76.4
2	Participant tried, but unable to complete	132	3.4
8	Refused	2	0.1
9	Not attempted for safety or health reasons	7	0.2
	Missing	782	20%

RPTCHRSTNDCOMP - Repeated chair stand: completion

Col 69

Value	Description	N	%
1	Test completed	2,915	74.6
2	Participant tried, but unable to complete	56	1.4
8	Refused	2	0.1
9	Not attempted for safety or health reasons	8	0.2
	Missing	924	23.7%

RPTCHRTIME - Repeated chair stand: time

Col 70

Repeated chair stand: time it took to rise out of a chair 5 times in succession (seconds).

Usage Notes:

Maximum possible time set to 60 seconds.

N	Missing	Min	Max	Mean	StdDev
2,878	1,027	4	60	16.767	9.193

BMI - Body-mass Index (BMI), kg/m2

Col 71

If a participant's BMI is greater than 70, BMI is missing.

N	Missing	Min	Max	Mean	StdDev
3,586	319	13.718	57.365	27.462	5.682

BMIC - Body-mass Index (BMI), kg/m2

Col 72

Computed from Form 301, height and weight. Reference: Expert Panel on the identification, evaluation, and treatment on overweight in adults (1998). Categorization of BMI into six groups. If a participant's BMI is greater than 70, BMIC is missing.

Value	Description	N	%
1	Underweight (< 18.5)	85	2.2
2	Normal (18.5 - 24.9)	1,232	31.5
3	Overweight (25.0 - 29.9)	1,289	33
4	Obesity I (30.0 - 34.9)	638	16.3
5	Obesity II (35.0 - 39.9)	225	5.8
6	Extreme Obesity III (>= 40)	117	3
	Missing	319	8.2%

LASPPB - Look AHEAD short physical performance battery score

Col 73

A continuous score (0-3) calculated as the sum of balance, chair stand, and gait speed ratios. See data prep document for details.

Usage Notes:

N	Missing	Min	Max	Mean	StdDev
2,544	1,361	0	3	1.535	0.53

EPESESPPB - EPESE short physical performance battery score

Col 74

A continuous score (0-12) calculated as the sum of balance, chair stand, and gait speed scores. See data prep document for details.

Usage Notes:

N	Missing	Min	Max	Mean	StdDev
2,766	1,139	0	12	7.345	2.682