This document can be used to prepare or evaluate feasibility of ancillary study proposals and paper proposals, but is NOT intended for publication.

DVT/PE Outcome Details (Form 126)

File NameData as ofPopulationData collectedOne row perRows
outc_dvt_pe_inv.dat2/17/2024HT,MRCMain, Ext1, Ext2Outcome Form2,269
ID - WHI Participant Common ID
Col 1
NMissing
2,2690
ASCSOURCE - Ascertainment Source
Col 2
ValueDescriptionN%
1Local Form 12670.3
2Central Form 1262,26299.7
DVT - DVT
Col 3

Deep Vein Thrombosis (DVT)

Usage Notes:

DVT is adjudicated for the Medical Record Super Cohort through Ext1. In Ext2 it is adjudicated for the Medical Record Cohort. Includes both outpatient and inpatient DVTs.

ValueDescriptionN%
0No00
1Yes1,52067
Missing74933%
PE - PE
Col 4

Pulmonary Embolism (PE)

Usage Notes:

Defined as the first occurrence of PE or a Death due to Pulmonary Embolism. PE was adjudicated for the Medical Record Super Cohort through Ext1. In Ext2 it is adjudicated for the Medical Record Cohort. See the DEATH and DEATHSRC variables for details about the death adjudication process.

ValueDescriptionN%
0No00
1Yes1,18852.4
Missing1,08147.6%
DVTDX - F126 DVT diagnosis
Col 5
Usage Notes:

Not collected on early versions of F126.

ValueDescriptionN%
1DVT not caused by procedure within 60 days1,17952
2DVT caused by procedure within 60 days32114.1
Missing76933.9%
DVTDISCH - F126 DVT based on hospital discharge summary
Col 6

DVT based on: hospital discharge summary with a diagnosis of deep vein thrombosis

ValueDescriptionN%
0No38517
1Yes1,13249.9
Missing75233.1%
DVTVENOG - F126 DVT based on positive findings on venogram
Col 7

DVT based on: positive findings on a venogram

ValueDescriptionN%
0No1,48665.5
1Yes311.4
Missing75233.1%
DVTPLETH - DVT positive findings impedance plethysmography
Col 8

DVT based on: positive findings using impedance plethysmography

ValueDescriptionN%
0No1,51266.6
1Yes50.2
Missing75233.1%
DVTDOPPL - F126 DVT positive findings on doppler
Col 9

DVT based on: positive findings on doppler duplex, ultrasound, sonogram, or other non-invasive test examination

Usage Notes:

Not collected on early versions of F126.

ValueDescriptionN%
0No1355.9
1Yes1,38260.9
Missing75233.1%
DVTISOTP - F126 DVT positive findings on isotope
Col 10

DVT based on: Positive findings on isotope scan

ValueDescriptionN%
0No1,51766.9
1Yes00
Missing75233.1%
DVTRPSRC - F126 diagnosis DVT report source
Col 11
Usage Notes:

Not collected on early versions of F126.

ValueDescriptionN%
1Hospital inpatient1,10448.7
2Hospital outpatient facility or clinic1787.8
3Radiology or imaging facility703.1
4Physician's office/private medical411.8
5Nursing/convalescent home/hospice40.2
6Autopsy only10
7Death Certificate only30.1
8Other70.3
Missing86137.9%
PEWORKUP - F126 PE work up done
Col 12

Was a work up for pulmonary embolism performed?

Usage Notes:

Not collected on early versions of F126.

ValueDescriptionN%
0No90.4
1Yes45920.2
8Unknown40.2
Missing1,79779.2%
PEDX - F126 PE diagnosis
Col 13
Usage Notes:

Not collected on early versions of F126.

ValueDescriptionN%
1PE not caused by procedure within 60 days90039.7
2PE caused by procedure within 60 days28012.3
Missing1,08948%
PEDISCH - F126 PE based on hospital discharge summary
Col 14

PE based on: hospital discharge summary with a diagnosis of pulmonary embolism

ValueDescriptionN%
0No974.3
1Yes1,09148.1
Missing1,08147.6%
PEVENTPR - F126 PE positive ventilation-perfusion
Col 15

PE based on: high probability on ventilation-perfusion lung scan (exclude moderate, intermediate, or low probability on ventilation-perfusion lung scan)

ValueDescriptionN%
0No98143.2
1Yes2079.1
Missing1,08147.6%
PEANGIO - F126 PE positive pulmonary angiogram
Col 16

PE based on: positive findings on pulmonary angiogram or spiral CT

ValueDescriptionN%
0No29613
1Yes89239.3
Missing1,08147.6%
PEGE1DVT - F126 PE based on >=1 DVT + PE signs/symptoms
Col 17

PE based on: Diagnosis of deep vein thrombosis (DVT) based on >=1 DVT criteria, plus signs and symptoms suggestive of PE (e.g., acute chest pain, dyspnea, tachypnea, hypoxemia, tachycardia, or chest X-ray findings suggestive of PE)

ValueDescriptionN%
0No94741.7
1Yes24110.6
Missing1,08147.6%
PEOTHER - F126 PE based on other, including autopsy
Col 18

PE based on: Other, including autopsy

Usage Notes:

Not collected on early versions of F126.

ValueDescriptionN%
0No1,05746.6
1Yes140.6
Missing1,19852.8%