7,875 women from the WHI Extension II Medical Records Cohort (MRC) participated in the WHI Long Life Study (LLS). The LLS consisted of a one-time in-person visit (conducted sometime between March 2012 and May 2013) with a blood draw, a brief clinical assessment, and an assessment of functional status. 14,081 MRC women were eligible for LLS (see below for eligibility requirements).
Please see the W64 (Long Life Study) Data page for more information.
LLS data and biospecimens are now available to researchers! The data and blood collected in the LLS establishes a new baseline from which numerous studies on aging and health/disease can be conducted. The data are comparable to WHI clinic data and they are now included in the WHI Investigator's Dataset (Form 301).Long Life Study (LLS)
[click here for the full eligible population description]
Table 1: Inclusion criteria by phase
In addition to the main in-person visit that collected physical measurements, functional measurements, and blood, the WHI Long Life Study included two funded ancillary studies: OPACH (AS286) and WHI-FI (AS340). These ancillary studies are described below.
OPACH - Objective Physical Activity and Cardiovascular Health in Women (PI Andrea LaCroix; AS286)
The goals of this study are to increase understanding of the health of aging women – specifically the association of physical activity with cardiovascular events and total mortality. The eligible population for OPACH is identical to the LLS with one exception: OPACH excluded women who were non-ambulatory. Participants who consented to LLS had the option of also consenting to OPACH on the same consent form. OPACH-specific activities include (1) wearing an accelerometer (physical activity monitor) for 1 week, (2) completing a Sleep Log for 1 week, (3) completing a Physical Activity Questionnaire, and (4) completing a Falls Calendar form every month for a year. OPACH activities will continue until one year after the last OPACH participant receives her OPACH 'kit'. While the LLS visits are complete, the OPACH activities will continue for many participants through 2014.
Two hundred OPACH participants completed an OPACH clinic visit for the OPACH Calibration Study. The women eligible for the Calibration Study were separately consented from OPACH.
WHI-Food Intake Study (WHI-FI) - Evidence for Establishing Optimum Protein Intake in Older Adults (PI Jeannette Beasley; AS340)
The WHI-FI Study also shares the LLS population. The LLS post-visit thank you letter packet introduced participants to the WHI-FI Study and requested that they complete a Food Frequency Questionnaire (FFQ). A total of 5,951 FFQs were returned by LLS participants.
For more information, please see the study pages for: [AS286 - OPACH] [AS340 - WHI-FI].