This document can be used to prepare or evaluate feasibility of ancillary study proposals and paper proposals, but is NOT intended for publication.

HRT Medication Adherence

File NameData as ofPopulationData collectedOne row perRows
adh_ht_inv.dat9/12/2005HTBaseline, MainParticipant Visit230,567
ID - WHI Participant Common ID
Col 2
NMissing
230,5670
ADHVTYP - Visit type for HRT adherence period
Col 3
ValueDescriptionN%
1Screening00
2Semi-Annual visit00
3Annual visit230,567100
4Non-Routine visit00
56 week HRT/4 week CaD call00
6Diet Intervention00
7Interim 33/33D00
8Amendment 33/33D00
ADHVY - Visit year for HRT adherence period
Col 4
NMissingMinMaxMeanStdDev
230,56701114.7912.549
STARTDY - Days from rand to start of HRT adherence period
Col 5
Days from randomization to start of HRT adherence period.
NMissingMinMaxMeanStdDev
230,56703653,6531,384.488930.941
ENDDY - Days from rand to end of HRT adherence period
Col 6
Days from randomization to end of HRT adherence period.
NMissingMinMaxMeanStdDev
230,56703644,0171,748.76931
ADHRATE - HRT medication adherence rate for the period
Col 7
NMissingMinMaxMeanStdDev
230,567005.9720.5340.449
COLLECT - Was adherence collection performed during period
Col 8
Were HRT pill bottles collected to allow adherence determination for period? If not, no adherence rate can be calculated.
ValueDescriptionN%
0No81,22335.2
1Yes149,34464.8
STOPHRT - Participant inactive in HRT interventin during period
Col 9
Was the participant inactive in the HRT intervention (i.e. not taking study pills) for all or part of the period.
ValueDescriptionN%
0No115,08649.9
1Yes115,48150.1
RESUMEHRT - Participant resumed HRT intervention during period
Col 10
Did the participant resume HRT intervention (start taking study pills) during this period after having stopped?
ValueDescriptionN%
0No229,60399.6
1Yes9640.4
LOST - Participant lost-to-follow-up during period
Col 11
Did the participant have a status of lost-to-follow-up during all or part of this HRT adherence period?
ValueDescriptionN%
0No228,85899.3
1Yes1,7090.7
DEAD - Participant deceased during period
Col 12
Did the participant have a status of deceased during all or part of this HRT adherence period?
ValueDescriptionN%
0No224,39497.3
1Yes6,1732.7
OPENLABEL - Were open label HRT meds dispensed during period
Col 13
Were any open label HRT medications dispensed to the participant during this period?
Usage Notes: Open label medications are not factored into the adherence rate calculation.
ValueDescriptionN%
0No226,31498.2
1Yes4,2531.8
ERT2PERT - Participant was switched from E-alone to E+P in period
Col 14
Participant was switched from the unopposed estrogen study group to the estrogen+progesterone study group during this period (January 1995), due to PEPI trial results indicating long-term adherence to estrogen was not feasible in women with a uterus.
ValueDescriptionN%
0No230,23699.9
1Yes3310.1